Labprice Bonzo Antibody

Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

Description: Bonzo Antibody: Human immunodeficiency virus (HIV) and simian immunodeficiency virus (SIV) require coreceptors, in addition to CD4, to infect target cells. Some G protein-coupled receptors including CCR5, CXCR4, CCR3, and CCR2b in the chemokine receptor family have been identified as HIV coreceptors. An orphan G protein-coupled receptor was recently cloned and designated Bonzo, STRL33 and TYMSTR, and identified as HIV and SIV coreceptor. Bonzo/STRL33 serves as coreceptor for SIV, HIV-2 and HIV-1. The messenger RNA of Bonzo/STRL33 is expressed in lymphoid tissues and activated peripheral blood lymphocytes.

Research area: Chemokines & Cytokines
Host species: Rabbit
Species reactivity: Human
Homology: N/A
Immunogen: Bonzo antibody was raised against a peptide corresponding to 15 amino acids near the amino terminus of human Bonzo/STRL33.
The immunogen is located within the first 50 amino acids of Bonzo.
Tested Applications: E, WB, IHC-P, IF
Applications: Bonzo antibody can be used for detection of Bonzo by Western blot at 0.5 μ
g/mL. Antibody can also be used for immunohistochemistry starting at 2.5 μ
g/mL. For immunofluorescence start at 20 μ
g/mL.
Antibody validated: Western Blot in human samples
Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.
Specificity: N/A
Positive control 1: Cat. No. 1306 - Human Spleen Tissue Lysate
Positive control 2: Cat. No. 10-901 - Human Spleen Tissue Slide
Positive control 3: N/A
Positive control 4: N/A
Positive control 5: N/A
Positive control 6: N/A
Predicted molecular weight: Predicted: 38 kDa
Observed: 43 kDa
MW explanation: N/A
Validation: N/A
Isoforms: N/A
Purification: Bonzo Antibody is affinity chromatography purified via peptide column.
Clonality: Polyclonal
Clone: N/A
Isotype: IgG
Conjugate: Unconjugated
Physical state: Liquid
Buffer: Bonzo Antibody is supplied in PBS containing 0.02% sodium azide.
Concentration: 1 mg/mL
NCBI official symbol: CXCR6
Accession #: AAB64221
Protein GI #: 2253422
NCBI gene ID#: 10663
NCBI official full name: chemokine (C-X-C motif) receptor 6
NCBI organism: Homo sapiens
SWISSPROT #: O00574

Bonzo antibody can be stored at 4˚
C for three months and -20˚
C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Optimal dilutions for each application to be determined by the researcher.