Labprice FAIM2 Antibody

Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

Description: FAIM2 Antibody: Programmed cell death regulates a number of biological processes such as normal organism development, tissue homeostasis, and removal of damaged cells. Disruption of this process has been implicated in a variety of diseases such as cancer. FAIM2 is a recently identified protein that can inhibit the apoptotic signal transduced by the Fas receptor but not from the related tumor necrosis factor-alpha death signal. In this respect, FAIM2 is functionally similar to the anti-apoptotic proteins FAIM, FLIP and Bcl-xL. FAIM2, a seven membrane spanning protein, can bind the Fas receptor but does not regulate Fas expression or inhibit binding of FADD to Fas. FAIM2 is widely distributed, but highly expressed in the hippocampus and other neural tissues. FAIM2 was also identified as the neural membrane protein 35 (NMP35) and its expression is known to be regulated by the Phosphatidylinositol 3-kinase-Akt/PKB pathway.

Research area: Apoptosis
Host species: Rabbit
Species reactivity: Human, Mouse, Rat
Homology: Predicted species reactivity based on immunogen sequence: Bovine: (94%)
Immunogen: FAIM2 antibody was raised against a 16 amino acid synthetic peptide from near the amino terminus of human FAIM2.
The immunogen is located within the first 50 amino acids of FAIM2.
Tested Applications: E, WB, IHC-P
Applications: FAIM2 antibody can be used for detection of FAIM2 by Western blot at 0.5 - 1 μ
g/mL. Antibody can also be used for immunohistochemistry starting at 5 μ
g/mL.
Antibody validated: Western Blot in mouse samples and Immunohistochemistry in mouse samples. All other applications and species not yet tested.
Specificity: N/A
Positive control 1: Cat. No. 1287 - EL4 Cell Lysate
Positive control 2: Cat. No. 1402 - Mouse Lung Tissue Lysate
Positive control 3: N/A
Positive control 4: N/A
Positive control 5: N/A
Positive control 6: N/A
Predicted molecular weight: N/A
MW explanation: N/A
Validation: N/A
Isoforms: N/A
Purification: FAIM2 Antibody is affinity chromatography purified via peptide column.
Clonality: Polyclonal
Clone: N/A
Isotype: IgG
Conjugate: Unconjugated
Physical state: Liquid
Buffer: FAIM2 Antibody is supplied in PBS containing 0.02% sodium azide.
Concentration: 1 mg/ml
NCBI official symbol: FAIM2
Accession #: AAF06327
Protein GI #: 6273281
NCBI gene ID#: 23017
NCBI official full name: Fas apoptotic inhibitory molecule 2
NCBI organism: Homo sapiens
SWISSPROT #: Q9BWQ8

FAIM2 antibody can be stored at 4˚
C for three months and -20˚
C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Optimal dilutions for each application to be determined by the researcher.