Labprice Bax AntibodyBiovision
Antigen alternative names: 581, BAX, 600040, P55269, Bax zeta
Immunogen sequence: Synthetic peptide corresponding to amino acids near the N-terminus of human Bax
Accession number: L22473
Purification: Affinity purified
Background information: The Bcl-2 (B-cell leukemia/lymphoma 2) family proteins function to either inhibit (Bcl-2 and Bcl-XL) or promote (Bax and Bak) apoptosis. Bax contains the conserved Bcl-2 homology 1 (BH1) and 2 (BH2) domains that allow for its homodimerization or heterodimerization with Bcl-2. When Bcl-2 is in excess, apoptosis is inhibited. However, if Bax levels increase in response to a death signal, the cell is pushed toward death.
Description: Rabbit Polyclonal antibody recognizing Human, mouse, rat, monkey antigen.
Species reactivity: Human, mouse, rat, monkey
Isotype: Rabbit IgG
Concentration: 0.5 mg/ml
Formulation: 30 µg (0.5 mg/ml) affinity purified rabbit anti-Bax polyclonal antibody in phosphate buffered saline (PBS), pH 7.2, containing 30% glycerol, 0.5% BSA, 0.01% thimerosal
Application: Western blot analysis (0.5-4 µg/ml), immunoprecipitation (10-20 µg/ml). However, the optimal conditions should be determined individually.The antibody detects a 20 kDa protein, corresponding to the apparent molecular weight of Bax on SDS-PAGE immunoblots.
Shipping: gel pack
Storage: -20 °C
Shelf life: 12 months
Handling: The antibody solution should be gently mixed before use.
For research use only.