Bcl-2-IN-2
TargetMol Chemicals
SMILES: CCc1ccccc1[C@@H]1CCCN1C1CC2(C1)CCN(CC2)c1ccc(C(=O)NS(=O)(=O)c2ccc(NC[C@H]3CC[C@](C)(O)CC3)c(c2)N(=O)=O)c(Oc2cnc3[nH]ccc3c2)c1 |wU:8.8,41.46,wD:38.41,41.45,(10.07,9.11,
9.75,10.61,
10.9,11.64,
12.36,11.17,
13.5,12.2,
13.18,13.7,
11.72,14.18,
10.58,13.15,
9.11,13.63,
8.64,15.09,
7.1,15.09,
6.62,13.63,
7.87,12.72,
7.87,11.18,
8.95,10.09,
7.87,9,
6.78,10.09,
9.2,8.23,
9.2,6.69,
7.87,5.92,
6.53,6.69,
6.53,8.23,
7.87,4.38,
9.2,3.61,
9.2,2.07,
7.87,1.3,
7.87,-.24,
6.53,-1.01,
9.2,-1.01,
10.53,-.24,
9.76,1.1,
11.3,-1.57,
11.87,.53,
13.2,-.24,
14.53,.53,
14.53,2.07,
15.87,2.84,
15.87,4.38,
17.2,5.15,
18.53,4.38,
19.87,5.15,
19.87,6.69,
20.4,8.14,
21.38,6.43,
18.53,7.46,
17.2,6.69,
13.2,2.84,
11.87,2.07,
13.2,4.38,
14.53,5.15,
11.87,5.15,
6.53,2.07,
5.2,1.3,
3.86,2.07,
3.86,3.61,
2.53,4.38,
1.2,3.61,
-.27,4.09,
-1.17,2.84,
-.27,1.6,
1.2,2.07,
2.53,1.3,
6.53,3.61,)|
Formula: C48H57N7O7S
Description: Bcl-2-IN-2
Purity: 0.98
CAS#: 2383085-86-5
Molecular Weight: 876.09
Bioactivity: Bcl-2-IN-2 is a potent and selective Bcl-2 inhibitor with an IC 50 of 0.034 nM and also inhibits Bcl-xL with an IC 50 of 43 nM, showing >1000-fold selectivity for Bcl-2 over Bcl-xL.
For research use only.