CPD-1224
MedChemExpress
Description: CPD-1224 is an orally active derivative of ALK inhibitors to cereblon ligands. CPD-1224 targets to EML4-ALK oncogenic fusions, and degrades ALK and mutant L1196M/G1202R[1].
CAS number: 2891620-68-9
Purity: 99.24
Formula: C43H47ClN8O7S
Solubility: DMSO : 14.29 mg/mL (ultrasonic
warming
heat to 160°C)
SMILES: ClC1=CN=C(NC2=C(OC)C=C(C3CCN(CC4CN(C5=CC=C6C(C(N(C7CCC(NC7=O)=O)C6=O)=O)=C5)C4)CC3)C(C)=C2)N=C1NC8=C(S(C(C)C)(=O)=O)C=CC=C8
Molecular Weight: 855.40
Applications: Cancer-Kinase/protease
-20°C, 3 years
4°C, 2 years (Powder)
For research use only. Not to be used for human or animal treatment or consumption.
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