ET receptor antagonist 1
MedChemExpress
Description: ET receptor antagonist 1 (compound 16h) is an orally active ET receptor antagonist (IC50=0.18 nM), which can be used for research in pulmonary arterial hypertension (PAH). ET receptor antagonist 1 attenuates monocrotaline (HY-N0750) induced PAH in rat model[1].
Formula: C21H25N5O5S
Solubility: 10 mM in DMSO
SMILES: CC(CCOC(N=C1C2=NC=CC=N2)=C(C(NS(=O)(C)=O)=N1)OC3=CC=CC=C3OC)C
Molecular Weight: 459.52
For research use only. Not to be used for human or animal treatment or consumption.
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