DT-061 (SMAP) Liposomes, Formulation TT-40

300 mM sucrose

Description: PEGylated liposomes containing PP2A activator DT-061 (SMAP). DT-061 is an activator of protein phosphatase 2A (PP2A). PP2A regulates many cellular signaling pathways including MAPK/ERK, Wnt/β-catenin, Akt/mTOR, GSK3β, p53/apoptosis, cell cycle, and others. This product can be used in vitro or in vivo for studying the effects of PP2A activation and could be applied to preclinical therapy of KRAS-mutant and MYC-driven tumors. The liposomes are PEGylated for optimal in vivo performance. For preclinical research use only.

4.0 mg/mL

PP2A pathway (regulates MAPK/ERK, Wnt/β-catenin, Akt/mTOR, GSK3β, p53/apoptosis. cell cycle, and other pathways)