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Anti-Phospho-CTNNB1-(S675) antibody
id: LP-STJ117893

Labprice Anti-Phospho-CTNNB1-(S675) antibody

St John's Laboratory


Description: The protein encoded by this gene is part of a complex of proteins that constitute adherens junctions (AJs). AJs are necessary for the creation and maintenance of epithelial cell layers by regulating cell growth and adhesion between cells. The encoded protein also anchors the actin cytoskeleton and may be responsible for transmitting the contact inhibition signal that causes cells to stop dividing once the epithelial sheet is complete. Finally, this protein binds to the product of the APC gene, which is mutated in adenomatous polyposis of the colon. Mutations in this gene are a cause of colorectal cancer (CRC), pilomatrixoma (PTR), medulloblastoma (MDB), and ovarian cancer. Alternative splicing results in multiple transcript variants.

Clonality: Polyclonal
Host: Rabbit
Conjugation: Unconjugated
Applications: WB
Reactivity: Human,Mouse,Rat
Formulation: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Purification: Affinity purification
Clone: NA
Concentration: NA
Gene: CTNNB1
Immunogen: A synthetic phosphorylated peptide around S675 of human CTNNB1 (NP_001091679.1).



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