Labprice Betacellulin Recombinant Protein
ProSci
Description: Betacellulin is an EGF-related polypeptide growth factor that signals through the EGF receptor. It is produced in several tissues, including the pancreas, small intestine, and in certain tumor cells. Betacellulin is a potent mitogen for retinal pigment epithelial cells and vascular smooth muscle cells. Betacellulin is initially synthesized as a glycosylated 32.0 kDa transmembrane precursor protein, which is processed by proteolytic cleavage to produce the mature sequence. Recombinant murine Betacellulin is a 9.0 kDa monomeric protein, containing 80 amino residues, which comprises the mature EGF homologous portion of the Betacellulin protein.
Tested Applications: N/A
Applications: N/A
Predicted Molecular Weight: N/A
Physical state: Lyophilized
Buffer: N/A
Concentration: N/A
NCBI official symbol: Btc
Accession #: NP_031594.1
Protein GI: 6680812
NCBI gene ID#: 12223
NCBI official full name: betacellulin, epidermal growth factor family member
NCBI organism: Mus musculus
Peptide sequence: DGNTTRTPET NGSLCGAPGE NCTGTTPRQK VKTHFSRCPK QYKHYCIHGR CRFVVDEQTP SCICEKGYFG ARCERVDLFY
SWISSPROT #: Q05928
Background Reference 1: N/A
Background Reference 2: N/A
Background Reference 3: N/A
Background Reference 4: N/A
Background Reference 5: N/A
Source: E. coli
Species: Murine
By Source: E. Coli
By Species: Mouse
Fusion tag: N/A
Sequence: DGNTTRTPET NGSLCGAPGE NCTGTTPRQK VKTHFSRCPK QYKHYCIHGR CRFVVDEQTP SCICEKGYFG ARCERVDLFY
Biology activity: Biological activity was determined by its ability to stimulate the proliferation of mouse Balb/3T3 cells. The expected ED50 is &le
0.01 ng/mL, corresponding to a specific activity of &ge
1 x 108 units/mg. Endotoxin level is less than 0.1 ng per µg (1EU/µg).
Purity: Greater than 98% by SDS-PAGE gel and HPLC analyses.
The lyophilized Betacellulin recombinant protein is stable for at least 2 years from date of receipt at -20°C. Reconstituted Betacellulin stable for at least 3 months when stored in working aliquots with a carrier protein at -20°C. As with any protein, exposing Betacellulin recombinant protein to repeated freeze / thaw cycles is not recommended. When working with proteins care should be taken to keep recombinant protein at a cool and stable temperature.
This product is for research use only.
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