Labprice CTGFL Recombinant Protein

Description: CTGFL/WISP-2 is a 24.3 kDa protein that belongs to the CCN family of cysteine rich regulatory proteins. Members of this family stimulate mitosis, adhesion, apoptosis, extracellular matrix production, growth arrest, and migration of multiple cell types. The protein is expressed in primary osteoblasts, fibroblasts, ovary, testes, and heart. In addition to promoting adhesion of osteoblasts, CTGFL/WISP-2 inhibits osteocalcin production, as well as binding of fibrinogen to integrin receptors. Recombinant human CTGFL/WISP-2 is a 24.3 kDa protein of 228 amino acid residues.

Tested Applications: N/A
Applications: N/A
Predicted Molecular Weight: N/A
Physical state: Lyophilized
Buffer: N/A
Concentration: N/A
NCBI official symbol: WISP2
Accession #: NP_003872.1
Protein GI: 4507923
NCBI gene ID#: 8839
NCBI official full name: WNT1 inducible signaling pathway protein 2
NCBI organism: Homo sapiens
Peptide sequence: MQLCPTPCTC PWPPPRCPLG VPLVLDGCGC CRVCARRLGE PCDQLHVCDA SQGLVCQPGA GPGGRGALCL LAEDDSSCEV NGRLYREGET FQPHCSIRCR CEDGGFTCVP LCSEDVRLPS WDCPHPRRVE VLGKCCPEWV CGQGGGLGTQ PLPAQGPQFS GLVSSLPPGV PCPEWSTAWG PCSTTCGLGM ATRVSNQNRF CRLETQRRLC LSRPCPPSRG RSPQNSAF
SWISSPROT #: O76076
Background Reference 1: N/A
Background Reference 2: N/A
Background Reference 3: N/A
Background Reference 4: N/A
Background Reference 5: N/A
Source: E. coli
Species: Human
By Source: E. Coli
By Species: Human
Fusion tag: N/A
Sequence: MQLCPTPCTC PWPPPRCPLG VPLVLDGCGC CRVCARRLGE PCDQLHVCDA SQGLVCQPGA GPGGRGALCL LAEDDSSCEV NGRLYREGET FQPHCSIRCR CEDGGFTCVP LCSEDVRLPS WDCPHPRRVE VLGKCCPEWV CGQGGGLGTQ PLPAQGPQFS GLVSSLPPGV PCPEWSTAWG PCSTTCGLGM ATRVSNQNRF CRLETQRRLC LSRPCPPSRG RSPQNSAF
Biology activity: The ED50 was determined by its ability to inhibit IGF - II induced proliferation of MCF - 7 is between 10 - 20 ng/mL in the presence of 15 ng/mL of human IGF - II.
Purity: Greater than 95% by SDS-PAGE gel and HPLC analyses.

Endotoxin level is less than 0.1 ng per µg (1EU/µg).

The lyophilized CTGFL recombinant protein is stable for at least 2 years from date of receipt at -20°C. Reconstituted CTGFL is stable for at least 3 months when stored in working aliquots with a carrier protein at -20°C. As with any protein, exposing CTGFL recombinant protein to repeated freeze / thaw cycles is not recommended. When working with proteins care should be taken to keep recombinant protein at a cool and stable temperature.

This product is for research use only.