Labprice ARTS Antibody

Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

Description: ARTS Antibody: Apoptosis is related to many diseases and development. Mitochondrial proteins, such as cytochrome c, Apaf-1, and AIF play important role in apoptosis. A novel mitochondrial septin-like protein was identified recently and designated ARTS for apoptosis related protein in TGF-beta signaling pathway. ARTS that is encoded by the human septin H5/PNUTL2/CDCrel2b gene is located to mitochondria and translocates to the nucleus when apoptosis occurs. ARTS is expressed in many tissues. It enhances cell death induced by TGF-beta and, to a lesser extent, by other apoptotic agents, such as TNF-α and Fas ligand.

Research area: Apoptosis
Host species: Rabbit
Species reactivity: Human
Homology: N/A
Immunogen: ARTS antibody was raised against a synthetic peptide corresponding to amino acids near the amino terminus of human ARTS.
The immunogen is located within the first 50 amino acids of ARTS.
Tested Applications: E, WB, IHC-P, IF
Applications: ARTS antibody can be used for detection of ARTS by Western blot at 2 μ
g/mL. A band at 32 kDa can be detected. Antibody can also be used for immunohistochemistry starting at 2 μ
g/mL. For immunofluorescence start at 20 μ
g/mL.
Antibody validated: Western Blot in human samples
Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.
Specificity: N/A
Positive control 1: Cat. No. 1302 - Human Lung Tissue Lysate
Positive control 2: Cat. No. 1306 - Human Spleen Tissue Lysate
Positive control 3: Cat. No. 1305 - Human Kidney Tissue Lysate
Positive control 4: Cat. No. 10-101 - Human Lung Tissue Slide
Positive control 5: N/A
Positive control 6: N/A
Predicted molecular weight: 32 kDa
MW explanation: N/A
Validation: N/A
Isoforms: N/A
Purification: ARTS Antibody is affinity chromatography purified via peptide column.
Clonality: Polyclonal
Clone: N/A
Isotype: IgG
Conjugate: Unconjugated
Physical state: Liquid
Buffer: ARTS Antibody is supplied in PBS containing 0.02% sodium azide.
Concentration: 1 mg/mL
NCBI official symbol: SEPT4
Accession #: AAG45673
Protein GI #: 12024871
NCBI gene ID#: 5414
NCBI official full name: septin 4
NCBI organism: Homo sapiens
SWISSPROT #: O43236

ARTS antibody can be stored at 4˚
C for three months and -20˚
C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Optimal dilutions for each application to be determined by the researcher.