Labprice MTCH2 Antibody

Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

Description: MTCH2 Antibody: Apoptosis plays a major role in normal organism development, tissue homeostasis, and removal of damaged cells. Disruption of this process has been implicated in a variety of diseases such as cancer. The Bcl-2 family of proteins is comprised of critical regulators of apoptosis that can be divided into two classes: those that inhibit apoptosis and those that promote cell death. MTCH2 is a member of the mitochondrial carrier protein family that catalyze the exchange of substrates across the inner mitochondrial membrane and is targeted by Bid, a pro-apoptotic Bcl-2 family member, in response to apoptotic signals, suggesting that MTCH2 may play a key role in the mitochondrial apoptosis pathway.

Research area: Apoptosis
Host species: Rabbit
Species reactivity: Human, Mouse
Homology: Predicted species reactivity based on immunogen sequence: Bovine: (75%)
Immunogen: MTCH2 antibody was raised against a 15 amino acid synthetic peptide near the amino terminus of human MTCH2.
The immunogen is located within amino acids 80 - 130 of MTCH2.
Tested Applications: E, WB, IHC-P, IF
Applications: MTCH2 antibody can be used for detection of MTCH2 by Western blot at 1 μ
g/mL. Antibody can also be used for immunohistochemistry starting at 5 μ
g/mL. For immunofluorescence start at 20 μ
g/mL.
Antibody validated: Western Blot in human samples
Immunohistochemistry in mouse samples and Immunofluorescence in mouse samples. All other applications and species not yet tested.
Specificity: N/A
Positive control 1: Cat. No. 1210 - HEK293 Cell Lysate
Positive control 2: N/A
Positive control 3: N/A
Positive control 4: N/A
Positive control 5: N/A
Positive control 6: N/A
Predicted molecular weight: N/A
MW explanation: N/A
Validation: N/A
Isoforms: N/A
Purification: MTCH2 Antibody is affinity chromatography purified via peptide column.
Clonality: Polyclonal
Clone: N/A
Isotype: IgG
Conjugate: Unconjugated
Physical state: Liquid
Buffer: MTCH2 Antibody is supplied in PBS containing 0.02% sodium azide.
Concentration: 1 mg/mL
NCBI official symbol: Mtch2
Accession #: NP_055157
Protein GI #: 5815347
NCBI gene ID#: 56428
NCBI official full name: mitochondrial carrier homolog 2 (C. elegans)
NCBI organism: Mus musculus
SWISSPROT #: Q791V5

MTCH2 antibody can be stored at 4˚
C for three months and -20˚
C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Optimal dilutions for each application to be determined by the researcher.