Labprice LRFN1 Antibody

Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

Description: LRFN1 Antibody: LRFN1 is one of a family of five transmembrane glycoproteins that are highly expressed in neuronal tissues. LRFN proteins share leucine-rich repeat (LRR)-immunoglobulin-like (Ig)-fibronectin type III (Fn)-transmembrane domain structure with other members of the LRR-Ig-Fn protein superfamily such as the Slitrk family of proteins. Expression of LRFN1, -3, and -4 mRNA was detected in embryonic neuronal cells, while Lrfn2 and Lrfn5 expression was primarily restricted to more mature cells. LRFN1, -2, and -4 bound to PDZ domains of postsynaptic PSD95, re-distributing PSD95 to the cell periphery. It has been suggested that the Lrfn proteins play a role in the developing and/or mature vertebrate nervous system. At least two isoforms of LRFN1 are known to exist.

Research area: Neuroscience
Host species: Rabbit
Species reactivity: Human, Mouse, Rat
Homology: N/A
Immunogen: LRFN1 antibody was raised against an 18 amino acid synthetic peptide near the carboxy terminus of human LRFN1.
The immunogen is located within amino acids 700 - 750 of LRFN1.
Tested Applications: E, WB, IHC-P, IF
Applications: LRFN1 antibody can be used for detection of LRFN1 by Western blot at 1 - 2 μ
g/mL. Antibody can also be used for immunohistochemistry starting at 2.5 μ
g/mL. For immunofluorescence start at 20 μ
g/mL.
Antibody validated: Western Blot in human samples
Immunohistochemistry in mouse samples and Immunofluorescence in mouse samples. All other applications and species not yet tested.
Specificity: This antibody is predicted to not cross-react with other members of the LRFN family.
Positive control 1: Cat. No. 1303 - Human Brain Tissue Lysate
Positive control 2: N/A
Positive control 3: N/A
Positive control 4: N/A
Positive control 5: N/A
Positive control 6: N/A
Predicted molecular weight: N/A
MW explanation: N/A
Validation: N/A
Isoforms: N/A
Purification: LRFN1 Antibody is affinity chromatography purified via peptide column.
Clonality: Polyclonal
Clone: N/A
Isotype: IgG
Conjugate: Unconjugated
Physical state: Liquid
Buffer: LRFN1 Antibody is supplied in PBS containing 0.02% sodium azide.
Concentration: 1 mg/mL
NCBI official symbol: LRFN1
Accession #: Q9P244
Protein GI #: 189028858
NCBI gene ID#: 57622
NCBI official full name: leucine rich repeat and fibronectin type III domain containing 1
NCBI organism: Homo sapiens
SWISSPROT #: Q9P244

LRFN1 antibody can be stored at 4˚
C for three months and -20˚
C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Optimal dilutions for each application to be determined by the researcher.