Labprice PLEKHM2 Antibody

Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

Description: PLEKHM2 Antibody: PLEKHM2, also known as SKIP, is a member of the M family of Pleckstrin homology domain-containing proteins. While little is known of PLEKHM2, a recent study examining differential gene expression in human hematopoietic stem cells has shown it to be specifically expressed in stem cells, suggesting that PLEKHM2 may play a role in erythroid commitment and development. Other studies have shown that PLEKHM2 is required for interaction with the Salmonella virulence factor SifA for Salmonella pathogenesis, suggesting that PLEKHM2 has cellular roles other than in the developing embryo.

Research area: Stem Cell
Host species: Rabbit
Species reactivity: Human, Mouse, Rat
Homology: N/A
Immunogen: PLEKHM2 antibody was raised against a 17 amino acid synthetic peptide from near the carboxy terminus of human PLEKHM2.
The immunogen is located within the last 50 amino acids of PLEKHM2.
Tested Applications: E, WB, IHC-P, IF
Applications: PLEKHM2 antibody can be used for detection of PLEKHM2 by Western blot at 0.5 μ
g/mL. Antibody can also be used for immunohistochemistry starting at 5 μ
g/mL. For immunofluorescence start at 20 μ
g/mL.
Antibody validated: Western Blot in rat samples
Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.
Specificity: N/A
Positive control 1: Cat. No. 1463 - Rat Brain Tissue Lysate
Positive control 2: Cat. No. 10-201 - Human Liver Tissue Slide
Positive control 3: N/A
Positive control 4: N/A
Positive control 5: N/A
Positive control 6: N/A
Predicted molecular weight: N/A
MW explanation: N/A
Validation: N/A
Isoforms: N/A
Purification: PLEKHM2 Antibody is affinity chromatography purified via peptide column.
Clonality: Polyclonal
Clone: N/A
Isotype: IgG
Conjugate: Unconjugated
Physical state: Liquid
Buffer: PLEKHM2 Antibody is supplied in PBS containing 0.02% sodium azide.
Concentration: 1 mg/mL
NCBI official symbol: PLEKHM2
Accession #: CAH72018
Protein GI #: 55666400
NCBI gene ID#: 23207
NCBI official full name: pleckstrin homology domain containing, family M (with RUN domain) member 2
NCBI organism: Homo sapiens
SWISSPROT #: Q8IWE5

PLEKHM2 antibody can be stored at 4˚
C for three months and -20˚
C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Optimal dilutions for each application to be determined by the researcher.