Labprice SLFN12 Antibody

Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

Description: SLFN12 Antibody: Despite being first described several years ago, the roles of the Schlafen (SLFN) family of proteins remain largely unknown. The SLFN genes are preferentially expressed in lymphoid tissues and differentially regulated during thymocyte maturation. It is thought that many play roles in cell growth, hemopoietic cell differentiation, and T cell development and maturation. Most members contain at least one divergent AAA domain (AAA_4) that may play a role in ATP binding. Although also known as SLFN3, a Schlafen family member that may be a marker of T cell activation, human SLFN12 has relatively low homology to SLFN3 in other species. Loss of the SLFN12 gene due to deletion is associated with Kabuki syndrome, a multiple congenital anomaly syndrome, suggesting SLFN may play a role in this genetic condition.

Research area: Immunology
Host species: Rabbit
Species reactivity: Human
Homology: N/A
Immunogen: SLFN12 antibody was raised against a 12 amino acid synthetic peptide from near the carboxy terminus human SLFN12.
The immunogen is located within the last 50 amino acids of SLFN12.
Tested Applications: E, WB
Applications: SLFN12 antibody can be used for detection of SLFN12 by Western blot at 1 μ
g/mL.
Antibody validated: Western Blot in human samples. All other applications and species not yet tested.
Specificity: N/A
Positive control 1: Cat. No. 1220 - SK-N-SH Cell Lysate
Positive control 2: N/A
Positive control 3: N/A
Positive control 4: N/A
Positive control 5: N/A
Positive control 6: N/A
Predicted molecular weight: N/A
MW explanation: N/A
Validation: N/A
Isoforms: N/A
Purification: SLFN12 Antibody is affinity chromatography purified via peptide column.
Clonality: Polyclonal
Clone: N/A
Isotype: IgG
Conjugate: Unconjugated
Physical state: Liquid
Buffer: SLFN12 Antibody is supplied in PBS containing 0.02% sodium azide.
Concentration: 1 mg/mL
NCBI official symbol: SLFN12
Accession #: NP_060512
Protein GI #: 157388955
NCBI gene ID#: 55106
NCBI official full name: schlafen family member 12
NCBI organism: Homo sapiens
SWISSPROT #: Q8IYM2

SLFN12 antibody can be stored at 4˚
C for three months and -20˚
C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Optimal dilutions for each application to be determined by the researcher.