Labprice SYNGR3 Antibody

Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

Description: SYNGR3 Antibody: Synaptogyrins comprise a family of tyrosine-phosphorylated membrane proteins with two neuronal (SYNGR1 and SYNGR3) and one ubiquitous (SYNGR2) members. SYNGR1 and -3 are synaptic vesicle proteins, residing in some cases on the same synaptic vesicle, and are thought to be involved in the regulation of neurotransmitter release. SYNGR2, by contrast, is absent from synaptic vesicles. The role and localization of a fourth synaptogyrin, SYNGR4, is unclear. SYNGR3 is predominantly expressed in brain and placenta. SYNGR3 is involved in the positive regulation of dopamine transporter activity and facilitates the physical and functional interactions of the transporter with the dopamine vesicular storage system, allowing a more efficient loading of the vesicles with extracellular dopamine after release.

Research area: Neuroscience
Host species: Rabbit
Species reactivity: Human, Mouse, Rat
Homology: Predicted species reactivity based on immunogen sequence: Bovine: (89%)
Immunogen: SYNGR3 antibody was raised against a 19 amino acid synthetic peptide from near the carboxy terminus of human SYNGR3.
The immunogen is located within the last 50 amino acids of SYNGR3.
Tested Applications: E, WB, IHC-P, IF
Applications: SYNGR3 antibody can be used for detection of SYNGR3 by Western blot at 1 - 2 μ
g/mL. Antibody can also be used for immunohistochemistry starting at 2.5 μ
g/mL. For immunofluorescence start at 20 μ
g/mL.
Antibody validated: Western Blot in mouse samples
Immunohistochemistry in rat samples and Immunofluorescence in rat samples. All other applications and species not yet tested.
Specificity: N/A
Positive control 1: Cat. No. 1403 - Mouse Brain Tissue Lysate
Positive control 2: N/A
Positive control 3: N/A
Positive control 4: N/A
Positive control 5: N/A
Positive control 6: N/A
Predicted molecular weight: N/A
MW explanation: N/A
Validation: N/A
Isoforms: N/A
Purification: SYNGR3 Antibody is affinity chromatography purified via peptide column.
Clonality: Polyclonal
Clone: N/A
Isotype: IgG
Conjugate: Unconjugated
Physical state: Liquid
Buffer: SYNGR3 Antibody is supplied in PBS containing 0.02% sodium azide.
Concentration: 1 mg/mL
NCBI official symbol: SYNGR3
Accession #: NP_004200
Protein GI #: 6631112
NCBI gene ID#: 9143
NCBI official full name: synaptogyrin 3
NCBI organism: Homo sapiens
SWISSPROT #: O43761

SYNGR3 antibody can be stored at 4˚
C for three months and -20˚
C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Optimal dilutions for each application to be determined by the researcher.