Labprice Mouse Transmembrane protein 98 (TMEM98) ELISA Kit

The intracellular signaling pathway by which TNF induces its pleiotropic actions is well-characterized and includes unique components, as well as modules shared with other signaling pathways. TMEM9B as an important component of TNF signaling and which is a module shared with the IL-1? and Toll-like receptor (TLR) pathways. is a glycosylated protein localized in membranes of the lysosome and partially in early endosomes. The expression of TMEM9B is required for the production of proinflammatory cytokines induced by TNF, IL-1?, and TLR ligands, but not for apoptotic cell death triggered by TNF or Fas ligand. TMEM9B is essential in TNF activation of both the NF-?B and MAPK pathways.TMEM9B is a key component of inflammatory signaling pathways and suggest that endosomal or lysosomal compartments regulate these pathways.

Description: This Mouse Transmembrane protein 98 (TMEM98) ELISA Kit employs a two-site sandwich ELISA to quantitate TMEM98.

Reactivity: Mouse
Sample types: serum, whole blood, plasma and other biological fluids
Detection range: Please inquire
Sensitivity: Please inquire Quantitative Sandwich ELISA
Method of detection: Colorimetric

Storage: The unopened kit should be stored at 2 - 8°C. After opening, please store refer to protocols.Shipping:Gel pack with blue ice.

This kit is intended for research use only. It should not be used for human or animal clinical diagnostics or treatment.